thank you for your answers.
One last question,
the dosage has now increased to 40mg zyprexa in combination with 600 mg of solian. Is this a safe dosage? Is it standard practice (her treating doc is very young)?My mother looks stiff (muscular stiffness) and is still in acute psychotic crisis (incoherent, agitated, sleeps one out of two nights and wakes up more confused and restless, and the results of the treatment are not visible at all). I understand that it take up to 8 wks efore we see results (meaning thinking clearly again), but not even a smaller improvment (like sleeping all nights) before these 8 weeks?
Thank you for your reply.
My mother is treated by a qualified psychiatrist who works in the Psychiatric hospital of Bucharest, Romania, where she lives . Without a psychiatrist?s prescription, it would have been impossible to even obtain (or know about) this meds. She is her treating psychiatrist for the last 7 years (before my mother was treated by the psychiatrist s mother, now retired), but is very young, around 35 and I doubt about her experience (not her good will).
Because it is Easter, we will hospitalize my mother from Tuesday on when all the activities/staffing will be normal. Indeed, my worry is that this high dosage might be safe at a hospital with all necessary facilities for a quick intervention in an emergency, but unsafe for home treatment as my father and myself do currently (although we communicate daily by phone with her treating doctor, who is on holidays, I still believe this kind of dosage should be monitored better).
We did not give her yet this dosage, but if your opinion, together with her own psychiatris?s is that it is safe, we will proceed this evening. My mother looks slightly better- although still totally confused, her eyes look clearer and her agitation is (maybe because of her zyprexa-introduced tiredness) reduced . Thank you
To her treatment:
a second doctor would recommend instead of her current combination,
30mg zyprexa per day and instead of solian one orifiril long 500
one pill plus abilify 1 pill every evening, would this be better?
what would be the early signs indicating her treatment is adequate ? (for example, does less agitation and a few hours of sleep per night mean we are going the right direction with the treatment or is it just the disease”s evolution?).
There are two possible risks with zyprexa : First hight blood sugar levels with severe problems and second state of confusion.
30 mg would be o.k. It is also an option to quit solian if it doesn´t improve the status and go for a trial with abilify (another neuroleptic drug). Orfiril long is a kind of mood stabilizer (and an antiepileptic drug). It is also used for mixed psychotic states and schizoaffective disorders.
There are always different treatment options. In my opinion it is best to trust the local psychiatrist but have different options of treatment in mind.